By Dr. Rer. Medic. (German Ph.D. equivalent) Anton Goetz
This image shows murine dendritic cells breaking down fluorescently-labeled gelatin with special structures on their cytoskeleton called podosomes. The gelatin is shown in green, the nucleus of the cells inis shown in blue, and the podosomes are the small red dots on the edge of the migrating dendritic cells.
Dendritic cells are the sentinels of the immune system. They reside throughout the body and, when they encounter pathogens, they become activated and migrate to the lymph nodes to show the pathogen to other cells of the immune system, like T cells, which initiate the immune response against the intruder.
Dr. Anton Goetz
NYU School of Medicine
Department of Microbiology
Division of Medical Parasitology
Ana Rodriguez’s Lab